What is GLP-1 & How Does It Reduce Appetite & Promote Weight Loss? | Dr. Andrew Huberman

So they stimulate the release of that or they are in fact a synthetic version of glucagon like peptide one . What is glucagon like peptide ? One , it is a peptide which is a small little protein that can dramatically suppress appetite .

What is GLP-1 & How Does It Reduce Appetite & Promote Weight Loss? | Dr. Andrew Huberman

And there are also new prescription drugs that are now hitting the market . And for which there are really impressive clinical trials for diabetes and obesity that are essentially glucagon like peptide one stimulator . So they stimulate the release of that or they are in fact a synthetic version of glucagon like peptide one .

What is GLP-1 & How Does It Reduce Appetite & Promote Weight Loss? | Dr. Andrew Huberman

And yet I actively avoid the smoked varieties of Yoruba mate because of the potential carcinogenic effects of the smoked varieties . Glucagon like peptide one as I mentioned earlier can suppress appetite . But what this paper shows is it does that by at least two mechanisms through parallel pathways .

What is GLP-1 & How Does It Reduce Appetite & Promote Weight Loss? | Dr. Andrew Huberman

And that's the principle of so called parallel pathways , parallel pathways as the name suggests are pathways that could be neural pathways or hormonal pathways or otherwise that operate independently of one another to accomplish a common goal . And what this paper really shows is that there's a set of peptides in the body and the peptide that I'm referring to today is called G LP one glucagon like peptide one and some related peptides . I've talked about these on the podcast before for two reasons .

What is GLP-1 & How Does It Reduce Appetite & Promote Weight Loss? | Dr. Andrew Huberman

And for which there are really impressive clinical trials for diabetes and obesity that are essentially glucagon like peptide one stimulator . So they stimulate the release of that or they are in fact a synthetic version of glucagon like peptide one . What is glucagon like peptide ?