I wanna make it clear that has not been examined specifically in the context of alcohol use disorder . But because a huge component of the negative effects of alcohol use disorder are based in this gut liver , brain access and disruption of the gut microbiome in the in inflammatory cytokines . It stands to reason that things that are well established to improve inflammation status .
And certainly for those that are chronic heavy drinkers , what you end up with is a situation in which you have inflammation in multiple places in the brain and body and the desire to drink even more and to further exacerbate that inflammation and the gut leaky ness . So this is basically a terrible scenario for the gut liver , brain access and it's especially prevalent in so called alcohol use disorder . Again , people , they're ingesting somewhere between 12 and 24 drinks per week .
Again , people , they're ingesting somewhere between 12 and 24 drinks per week . For those of you that are interested in learning more about the gut liver brain axis and in particular alcohol use disorder , I'll provide a link in the show note captions and there's a wonderful review on this , that details that but on the positive side , it points to the possibility that at least some , again , at least some of the negative effects of alcohol consumption , whether or not you're somebody who's currently ingesting alcohol or who used to ingest alcohol and is trying to so called repair these systems of the brain and body , whether or not replenishing the gut microbiota is gonna be beneficial . And we know that there are ways to do that and we know that there's at least some promise for the ability for the system to repair itself .
Again , of this sorts of patterns of drinking I talked about before . And certainly for those that are chronic heavy drinkers , what you end up with is a situation in which you have inflammation in multiple places in the brain and body and the desire to drink even more and to further exacerbate that inflammation and the gut leaky ness . So this is basically a terrible scenario for the gut liver , brain access and it's especially prevalent in so called alcohol use disorder .
I mean , you take in something that disrupts two systems , the gut microbiota and it disrupts in two ways , it's killing the good gut microbiota and it's allowing the bad bacteria to move from the gut into the bloodstream . You've also got pro inflammatory cytokines coming from the liver and those converge or arrive in the brain and create a system in which the neural circuits cause more drinking . That's a bad situation .
