Summary
The experiment focused on caloric restriction and its effect on lifespan. It found that distributing calories throughout the day and night extended lifespan by 10% in mice, while restricting calories to the active cycle (daytime) extended lifespan by 20%. This suggests that time-restricted feeding, which is a form of caloric restriction, may have potential health benefits and could potentially extend human lifespan. However, no specific biomarkers were found to predict the benefits of caloric restriction.