Animal goes samples each one licks a couple of licks and then , uh uh that's the one I want because it's appetitive and because I love it . So it prefers sugar to artificial sweetener . No , no , no , no , no .
Our need , our desire for sugar is because they beautifully work on the tongue . The liking to recognize sweet versus non sweet , but they failed to activate the key sensors in the cat that now inform the brain you get sugar . No need to crave more .
Let me tell you it about the gut brain axis and our insatiable appetite for sugar and fat , insatiable for sugar and quenchable for fat . And this is a story about the fundamental difference between liking and wanting like in sugar is the function of the taste system . And it's not really liking sugar .
The first clue is that it takes a long time to develop immediately suggesting a post ingested effect . So we reason if this is true and is the gut brain axis that's driving sugar preference , then there should be a group of neurons in the brain that are responding to post ingested sugar . And lo and behold , we identify a group of neurons in the brain that does this and these neurons receive their input directly from the gut brain axis from other neurons .
OK . Now let me just take it one step further and this now sugar molecules activate this unique gut brain circuit that now drives the development of our preference for sugar . Now , a key element of this circuit is that the sensors in the gut that recognize the sugar do not recognize artificial sweeteners at all .
