And this work is work of my own laboratory . You know , that began long ago when we discovered the sweet receptors and you can now engineer mice that lack these receptors . So in essence , these animals will be unable to taste sweet a life without sweetness .
But that's simply because artificial sweeteners have some off tastes . But as far as the sweet receptor is concerned , they both activate the same receptor , trigger the same signal . And if you give an animal , an option of a bottle containing sugar or sweetener versus water .
Our need , our desire for sugar is because they beautifully work on the tongue . The liking to recognize sweet versus non sweet , but they failed to activate the key sensors in the cat that now inform the brain you get sugar . No need to crave more .
Now , we're gonna take the mice and we're going to genetically engineer it to remove the sweet receptors . So these mice no longer have in their oral cavity , any sensors that can detect sweetness , be that sugar molecule , be it an artificial sweetener ? Be it anything else that tastes sweet ?
All right . Now , we're gonna take the mice and we're going to genetically engineer it to remove the sweet receptors . So these mice no longer have in their oral cavity , any sensors that can detect sweetness , be that sugar molecule , be it an artificial sweetener ?
