Impact of Drinking Alcohol & Smoking Nicotine & Marijuana on Fertility | Dr. Andrew Huberman

I think a lot of people aren't aware of just how striking an effect these certain behaviors that you want to avoid can have in diminishing your fertility for both males and females . So let's talk about those .

Impact of Drinking Alcohol & Smoking Nicotine & Marijuana on Fertility | Dr. Andrew Huberman

But more importantly , it increases what are called reactive oxygen species in the seminal fluid in the semen that contain the sperm . This very under normal circumstances , under healthy circumstances , beautifully orchestrated chemistry of fluid that allows a sperm to thrive in their trajectory and attempt to fertilize the egg and lead to a healthy pregnancy . So if you are a smoker and you want to conceive the best advice I can give you is to quit smoking .

Impact of Drinking Alcohol & Smoking Nicotine & Marijuana on Fertility | Dr. Andrew Huberman

The biology tells us the epidemiology tells us that this is just a terrible idea . It's going to reduce the likelihood of fertility and successful pregnancy . And if there is a successful pregnancy , the word success needs to be in quotes .

Impact of Drinking Alcohol & Smoking Nicotine & Marijuana on Fertility | Dr. Andrew Huberman

One bout of 5 to 6 drinks . If you're a woman or you're a man greatly increases both the likelihood of mutations in the embryo that would result from a fertilization . And at the same time , for reasons that should be obvious to you based on all the biology , we've talked about a greatly reduced probability of fertilization .

Impact of Drinking Alcohol & Smoking Nicotine & Marijuana on Fertility | Dr. Andrew Huberman

And therefore , I haven't yet ovulated . Ah , but if you remember the biology , we talked about earlier , specifically , there is a subset of follicles and eggs that leave that ovarian reserve quite a bit before that one egg is selected for and ovulates . And of course , there are all the different hormonal cascades in the general milieu of the ovary , which are important and are being regulated by different hormones .