How Marijuana Affects the Brain & Body | Dr. Andrew Huberman

So I know that a number of people depend on whether or not they get tested for work or for sport or otherwise for cannabis or CBD . And THC don't take this as a strict number , but typically if one ingests CBD or THC smokes cannabis ingests by orally , et cetera , it doesn't matter , it's gonna stay in that fatty tissue and can be detected for at least as long as 80 days after ingestion . And there's a whole industry as to , you know , how to accelerate the clearance .

How Marijuana Affects the Brain & Body | Dr. Andrew Huberman

Although there's some variation on that depending on individual metabolism , whether or not somebody is uh familiar with the compound , believe it or not , psychologically familiar , but also biologically familiar or whether or not it's a first time use or occasional use and so on . THC and CBD and other components of cannabis are highly what we call lipophilic . That is they have an affinity toward and they can actually pass through fatty tissues .

How Marijuana Affects the Brain & Body | Dr. Andrew Huberman

Now , this is all changing quite a lot nowadays because of the commercialization of THC and CBD products and cannabis in a number of different areas including in the United States . But still many people are ingesting cannabis THC CBD through sources where they don't really know how much they're bringing into their system . And so whether or not someone gets incredible anxiety relief , enhanced sense of mood and focus and well being pain relief , et cetera or whether or not they have full blown panic attacks , et cetera is very hard to predict based on dosage information alone .

How Marijuana Affects the Brain & Body | Dr. Andrew Huberman

So this is interesting , right ? We have the same compounds THC and or CBD brought into the body and brain binding the same receptors . In this case , the CB one receptors .

How Marijuana Affects the Brain & Body | Dr. Andrew Huberman

That is absolutely categorically false . Everything we know about the way that THC and CBD work is that they tend to potentiate that is increase the effects of these different systems at given synapses and in different areas of the brain and body . That is if someone experiences paranoia or anxiety from a given strain of the marijuana plant or from ingesting an edible in a particular way or a particular kind of edible , that person is very likely to experience the same effect every time they ingest that strainer variety , this is part of what's led to this enormous industry .