So eventually he got out of this prison , as we , as we mentioned in 1945 . And he started doing experiments in addition to seeing patients in his clinic . And what he did is he started to take urine from people who exhibited mania and urine from people who are not manic .
This is getting pretty wild and pretty weird , but this is medicine and from time to time this is medicine and science . Cade was a good scientist in addition to being a good physician and by good scientists , I mean that he did control experiments here . He was injecting lithium rate into animals and see an effect .
And what he did is he started to take urine from people who exhibited mania and urine from people who are not manic . And he took that urine and he would inject it into guinea pigs as an experimental model . And his general observation was that there was something in the urine that was indeed making the guinea pigs more manic if they were injected with urine from a manic patient , right ?
And so he quite appropriately asked , maybe the lithium alone is having this calming effect on these guinea pigs . And indeed , that was the case when he did the proper control experiment and injected only lithium solution into these guinea pigs . They calm down from there .
And his general observation was that there was something in the urine that was indeed making the guinea pigs more manic if they were injected with urine from a manic patient , right ? The exact measures that he was taking in these guinea pigs wasn't exactly clear . This is um at a time or an era in science when you could uh just sort of report things a little bit more subjectively .
