Well , this now becomes the germane question . There is no ambiguity that A ob is causally related to atherosclerosis . You know how , how , how can I tell you that I can tell you that looking at all of the clinical trial literature , all of the epidemic epidemiologic literature and perhaps even most importantly , the Mendelian randomization , all of these things tell us because by Mendelian randomization , meaning genetic mutants , humans out there that make very little ABO B or access .
And there's no ambiguity . LDL is causally related LDL cholesterol or a ob causally related to atherosclerosis . Well , if that's true and I haven't seen a credible argument that it's not , there are people who argue that it's not by the way , but they just don't have credibility in their arguments , then you have to say that what we're doing in medicine today is very backwards because what we're doing in medicine today is the following .
If the CT angiogram shows no evidence of calcification , no evidence of soft plaque . That means grossly , their coronary arteries are still normal histologically , they're probably not because nobody probably makes it to our age with histologically perfect coronary arteries . You know , we might be satisfied with a person's a ob being at the fifth percentile of the population , which would be about 60 mg per deciliter .
You know , we might be satisfied with a person's a ob being at the fifth percentile of the population , which would be about 60 mg per deciliter . But if we have any other factors , meaning we're starting later in life , you know , or a person already has gross evidence of disease , calcification , soft plaque , family history is significant . Any other risk factors are present ?
So , and we have calculators that are pretty good at predicting your 10 year event risk . They'll look at your cholesterol levels , your blood pressure , they'll ask if you smoke , they'll ask some family history questions and they'll spit out a number . Now , we should do yours after the fact .
