The occasional energy drink , things of that sort , caffeine does many things besides stimulate our central nervous system and make us feel less sleepy . However , one of the things that caffeine does is it is a fairly potent PDE inhibitor by being a potent PDE inhibitor . It indirectly stimulates IGF one .
Why ? Well , because PDE can suppress IGF one and by ingesting caffeine or by applying topical caffeine ointment or cream to the scalp , you can suppress PDE sufficiently enough to increase IGF one and increase some hair growth or at least maintain hair growth in that region . This may come as a shock .
We're still in the early stages of all this . But I do think it's important to mention caffeine because of the lower incidence of side effects , at least reported side effects and the general safety margins and the head to head essentially comparable efficacy with monoxide because monoxide has a bunch of other issues . Now , keep in mind that both men and caffeine are generally used as a preventative for reducing hair loss over time .
So that's why you have to rely on the application of these caffeine ointments about three times a week . Keep in mind that no one has really explored the dosages of caffeine in these ointments in a systematic way . We're still in the early stages of all this .
Please put that in the comment section . I'd be curious about those experiences but as far as I know and from the clinical literature that I read , there's no examples of that one other point about caffeine , it does appear that caffeine can not only indirectly stimulate IGF one in the antigen phase of hair cell growth by way of reducing PDE and TGF beta . But it also seems to reduce a ptosis which is naturally occurring cell death of that stem cell niche .