They are not expected and they do not as far as we know , create new hair growth to any sufficient degree . If any of you have used caffeine ointments or minoxidil and observed new hair growth that was robust . Please put that in the comment section .
Why ? Well , because PDE can suppress IGF one and by ingesting caffeine or by applying topical caffeine ointment or cream to the scalp , you can suppress PDE sufficiently enough to increase IGF one and increase some hair growth or at least maintain hair growth in that region . This may come as a shock .
The concentration of caffeine in different ointments varies tremendously . Most of the studies of caffeine on the stem cell niches that control hair growth and extension of the antigen phase of hair growth have been performed in vitro in a dish . Although there are some clinical studies exploring this , they are not nearly as extensive in number or duration as the studies of Minoxidil because this approach just hasn't been around quite as long .
I will include a reference to caffeine and its uses for offsetting hair loss . Keep in mind that topical caffeine ointments shouldn't necessarily be applied every single day . So this is the sort of thing you might do three times a week .
But head to head , topical caffeine application can be as effective as monoxide application without actually lowering things like blood pressure and potentially increasing prolactin and some of the other negative let's call them negative because they are side effects of monoxide . So , caffeine ointments and caffeine present in various hair treatments and creams , et cetera is starting to become a more prominent theme out there . I will include a reference to caffeine and its uses for offsetting hair loss .
