How Does Alcohol Increase the Risk of Cancer? | Dr. Andrew Huberman

But I do want to emphasize that if that equates to seven drinks per week and all those seven drinks are being consumed on Friday and Saturday , it still averages to 10 g per day . And I also want to emphasize that there are things that people can do to at least partially offset some of the negative effects of alcohol as it relates to predisposition to the formation of certain kinds of tumors and cancers . I also want to be clear before I say it that doing the things I'm about to tell you is not a guarantee that you're not going to get cancer , nor is it a guarantee that alcohol is not going to lead to an increased predisposition for certain kinds of cancers .

How Does Alcohol Increase the Risk of Cancer? | Dr. Andrew Huberman

And the two things are consumption of folate and other B vitamins , especially B 12 . You know , the the consumption of folate and B 12 has been shown to decrease cancer risk in people that ingest alcohol but not completely offset it . Why ?

How Does Alcohol Increase the Risk of Cancer? | Dr. Andrew Huberman

One of the really bad effects of alcohol . But that's extremely well documented is the fact that alcohol because of this toxicity of acetyl aldehyde and related pathways can alter DNA methylation .

How Does Alcohol Increase the Risk of Cancer? | Dr. Andrew Huberman

Again , the literature doesn't support that . But also , again , there aren't a lot of studies but more to the point as it relates to alcohol in the formation of tumors and cancers , it does appear that decreased folate and other B vitamins like B 12 are partially responsible for the effect of alcohol and increasing cancer risk . And it does appear that consuming adequate amounts of folate and B 12 might again , might partially really want a bold face and underline and highlight , partially offset some of that increased risk .

How Does Alcohol Increase the Risk of Cancer? | Dr. Andrew Huberman

One of the really bad effects of alcohol . But that's extremely well documented is the fact that alcohol because of this toxicity of acetyl aldehyde and related pathways can alter DNA methylation . It can alter gene expression .