How Does Alcohol Increase the Risk of Cancer? | Dr. Andrew Huberman

And the two things are consumption of folate and other B vitamins , especially B 12 . You know , the the consumption of folate and B 12 has been shown to decrease cancer risk in people that ingest alcohol but not completely offset it . Why ?

How Does Alcohol Increase the Risk of Cancer? | Dr. Andrew Huberman

But also , again , there aren't a lot of studies but more to the point as it relates to alcohol in the formation of tumors and cancers , it does appear that decreased folate and other B vitamins like B 12 are partially responsible for the effect of alcohol and increasing cancer risk . And it does appear that consuming adequate amounts of folate and B 12 might again , might partially really want a bold face and underline and highlight , partially offset some of that increased risk .

How Does Alcohol Increase the Risk of Cancer? | Dr. Andrew Huberman

Why ? That is , isn't exactly clear , it probably has something to do with the relationship between FOLATE and B 12 and other B vitamins in gene regulation pathways that can lead to tumor growth at some point soon , we will get an expert in cancer biology and in particular in breast cancer biology on the program and we can ask them about this . But I realize this is going to raise a number of questions and maybe even cause some of you to go out there and start taking folate and other B vitamins and B 12 .

How Does Alcohol Increase the Risk of Cancer? | Dr. Andrew Huberman

Again , the literature doesn't support that . But also , again , there aren't a lot of studies but more to the point as it relates to alcohol in the formation of tumors and cancers , it does appear that decreased folate and other B vitamins like B 12 are partially responsible for the effect of alcohol and increasing cancer risk . And it does appear that consuming adequate amounts of folate and B 12 might again , might partially really want a bold face and underline and highlight , partially offset some of that increased risk .

How Does Alcohol Increase the Risk of Cancer? | Dr. Andrew Huberman

That can mean many things in different tissues . But it is associate with a significant increase in cancer risk in particular , breast cancer . And in particular because breast tissue is present in both males and females , but in women , it's especially vulnerable to some of the DNA methylation changes .